But if Flegr is right, the 'latent' parasite may be quietly tweaking the connections between our neurons, changing our response to frightening situations, our trust in others, how outgoing we are, and even our preference for certain scents. And that’s not all. He also believes that the organism contributes to car crashes, suicides, and mental disorders such as schizophrenia. When you add up all the different ways it can harm us, says Flegr, 'Toxoplasma might even kill as many people as malaria, or at least a million people a year.'
An evolutionary biologist at Charles University in Prague, Flegr has pursued this theory for decades in relative obscurity. Because he struggles with English and is not much of a conversationalist even in his native tongue, he rarely travels to scientific conferences. That 'may be one of the reasons my theory is not better known,' he says. And, he believes, his views may invite deep-seated opposition. 'There is strong psychological resistance to the possibility that human behavior can be influenced by some stupid parasite,' he says. 'Nobody likes to feel like a puppet. Reviewers [of my scientific papers] may have been offended.' Another more obvious reason for resistance, of course, is that Flegr’s notions sound an awful lot like fringe science, right up there with UFO sightings and claims of dolphins telepathically communicating with humans.
But after years of being ignored or discounted, Flegr is starting to gain respectability. Psychedelic as his claims may sound, many researchers, including such big names in neuroscience as Stanford’s Robert Sapolsky, think he could well be onto something. Flegr’s 'studies are well conducted, and I can see no reason to doubt them,' Sapolsky tells me. Indeed, recent findings from Sapolsky’s lab and British groups suggest that the parasite is capable of extraordinary shenanigans. T. gondii, reports Sapolsky, can turn a rat’s strong innate aversion to cats into an attraction, luring it into the jaws of its No. 1 predator. Even more amazing is how it does this: the organism rewires circuits in parts of the brain that deal with such primal emotions as fear, anxiety, and sexual arousal. 'Overall,' says Sapolsky, 'this is wild, bizarre neurobiology.' Another academic heavyweight who takes Flegr seriously is the schizophrenia expert E. Fuller Torrey, director of the Stanley Medical Research Institute, in Maryland. 'I admire Jaroslav for doing [this research],' he says. 'It’s obviously not politically correct, in the sense that not many labs are doing it. He’s done it mostly on his own, with very little support. I think it bears looking at. I find it completely credible.'
What’s more, many experts think T. gondii may be far from the only microscopic puppeteer capable of pulling our strings. 'My guess is that there are scads more examples of this going on in mammals, with parasites we’ve never even heard of,' says Sapolsky."
Article in its entirety: "How Your Cat Is Making You Crazy"